Method of Stabilizing Antigen Emulsion Used in VDRL Syphilis Tests

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Comparison of the VDRL slide, TPI, and FTA-ABS tests in experimental syphilis in rabbits.

The first serological test for syphilis, developed by Wassermann, Neisser, and Bruck (1906), was a complement-fixation test for reagin activity. Many tests for reagin activity have been developed since then, including the Kline, Kahn, Hinton, Kolmer, Mazzini, and VDRL slide tests. However, none of these is absolutely specific for syphilis. The VDRL slide test (Harris, Rosenberg, and Riedel, 194...

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15 صفحه اول

The VDRL tube flocculation test; a microflocculation test for syphilis using cardiolipin-lecithin-cholesterol antigen.

In an earlier paper in this Journal (Vogelsang, 1947), a new microflocculation test for syphilis described by Harris, Rosenberg, and Riedel (1946) was compared with the Wassermann reaction, the Kahn standard test, and the Meinicke clarification test in 5,556 sera. The test was found to be very useful in the diagnosis of syphilis, having a satisfactory sensitivity and a good specificity. Harris ...

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VDRL titres in early syphilis before and after treatment.

OBJECTIVE To observe the pretreatment VDRL titres in different stages of early syphilis and evaluate the changes in VDRL titre following treatment using different treatment schedules. DESIGN Retrospective study was carried out by analysing the records of cases of early syphilis treated between 1976 to 1981. SETTING Armed Forces personnel treated at different service hospitals in India. SU...

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VDRL slide flocculation reaction for syphilis performed on active sera.

The discovery of cardiolipin (Pangborn, 1941a) as the active agent in antigens for sero-reactions for syphilis enabled the production of chemically defined antigens, composed of cardiolipin, purified lecithin (Pangborn, 1941b), and cholesterol. Among the many tube and slide flocculation reactions based on the use of cardiolipin antigens, the Venereal Disease Research Laboratory (VDRL) slide flo...

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ژورنال

عنوان ژورنال: Public Health Reports (1896-1970)

سال: 1958

ISSN: 0094-6214

DOI: 10.2307/4590254